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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MET
All Species:
22.42
Human Site:
T977
Identified Species:
61.67
UniProt:
P08581
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08581
NP_000236.2
1390
155541
T977
R
Y
D
A
R
V
H
T
P
H
L
D
R
L
V
Chimpanzee
Pan troglodytes
Q2QLF1
1390
155551
T977
R
Y
D
A
R
V
H
T
P
H
L
D
R
L
V
Rhesus Macaque
Macaca mulatta
NP_001162100
1381
154449
T977
R
Y
D
A
R
V
H
T
P
H
L
D
R
L
V
Dog
Lupus familis
XP_533823
1410
153277
L994
R
R
Q
L
V
L
S
L
N
S
N
D
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P16056
1379
153530
T975
R
Y
D
A
R
V
H
T
P
H
L
D
R
L
V
Rat
Rattus norvegicus
P97523
1382
153923
T978
R
Y
D
A
R
V
H
T
P
H
L
D
R
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07E01
1382
154611
T978
R
Y
D
P
R
V
H
T
P
H
L
D
R
L
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001163830
1425
157559
I985
W
Y
D
G
R
G
H
I
Q
H
L
D
R
L
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190267
1321
146315
E923
L
L
Q
V
P
R
P
E
G
I
G
N
T
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
35.1
N.A.
88.8
87.7
N.A.
77.3
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.8
98.7
52.2
N.A.
94.4
93.5
N.A.
86.6
N.A.
N.A.
N.A.
66
N.A.
N.A.
N.A.
48.9
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
0
0
0
0
0
0
0
0
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
78
0
0
0
0
0
0
0
0
89
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
12
0
0
12
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
78
0
0
78
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
12
0
12
0
12
0
12
0
0
78
0
12
78
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
12
12
0
0
0
% N
% Pro:
0
0
0
12
12
0
12
0
67
0
0
0
0
12
0
% P
% Gln:
0
0
23
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
78
12
0
0
78
12
0
0
0
0
0
0
78
0
0
% R
% Ser:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
67
0
0
0
0
12
0
0
% T
% Val:
0
0
0
12
12
67
0
0
0
0
0
0
0
0
67
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
78
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _